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Over 10 years of research and persistency. Please help fund treatments and cures for PJS, Polyposis, and LKB1/STK11.
Peutz-Jeghers Syndrome (PJS) is a genetic disorder characterized by development of uncontrolled polyp formation and proliferation, including pigmentations on the mouth and lips, and predisposition to cancer of all types. PJS is caused by mutation of the STK11/LKB1 essential tumor suppressor gene. Patients with PJS have 93% increase in life-time risk of developing cancer of the GI tract, liver, pancreas, lungs, breast, ovaries, uterus, testes, and other organs. They also endure consistent medical procedures, polyps, intussusception, internal bleeding, and GI blockages that are life threatening if not operated on immediately.
Other diseases linked to LKB1 (STK11) gene mutations include but are not limited to Lung Cancer ("According to the American Cancer Society, an estimated 606,520 Americans will die from cancer in 2020. This equates to 1,680 people dying of cancer each day in 2020, and 70 dying each hour."), Tuberous Sclerosis, Pancreatic Cancer, Breast Cancer, Stomach Cancer, Small intestine Cancer, Cervical Cancer, Uterine Cancer, Testicular Cancer, Esophageal Cancer, Alzheimer's disease, Cowden Syndrome, Bannayan-Riley-Ruvalcaba Syndrome, Lhermitte-Duclos disease, Proteus Syndrome, Polycystic Kidney disease, Obesity & Type 2 Diabetes, Cardiac Hypertrophy, Cardiovascular disease, Proteus Syndrome.
Our accelerated Research and Development consists of Scopes of Work (SOWs) focused on developing and producing safe and effective drugs and treatments for LKB1 (STK11) tumor suppressor gene mutation, Peutz Jeghers Symptoms, Polyposis and many other diseases.
We are proud to collaborate with Smart Patients, an online community for patients and their families affected by Peutz-Jeghers Syndrome PJS, Polyposis, and Tumor Suppressor Gene Mutations.
Our Mission is to Cure LKB1 (STK11) tumor suppressor gene mutation, Peutz Jeghers Syndrome, and provide treatments for Polyposis with efficient means that are collaborative, faster and less expensive.
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